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Multiple Myeloma: Commonest Form Of Blood Cancer!

Multiple Myeloma is the commonest form of cancer of blood cells, accounting for 15 per cent of all blood cancers. There are about 2500 new cases per annum in the UK, giving rise to 10-15,000 patients with the condition at any one time. The overall incidence is rising, and is higher in Afro-Caribbeans.

Multiple myeloma is treatable, but it cannot be considered a curable condition.

Types of Myeloma
There is really only one main type of myeloma, but in different people, the cancerous plasma cells make different antibodies. Doctors more often call these antibodies 'immunoglobulins'. In each case of myeloma, only one type of immunoglobulin is overproduced, but this varies from patient to patient. There are 5 basic immunoglobulins - A, G, M, D and E. In myeloma, the commonest one that is overproduced is IgG and the rarest IgE.

Controlling your symptoms
Even if it is not possible to get your myeloma into remission, you can have treatment to help control the symptoms it causes. This may be mild chemotherapy to damp it down. Or you may have radiotherapy to any trouble spots in your bones. Bisphosphonates can also be used to try to slow down the progress of the myeloma. And to reduce the levels of calcium in your blood if this is too high. Your doctor may suggest a treatment called plasma pharesis if the level of abnormal immunoglobulin protein is too high in your blood. Too much protein in the blood can make it too thick and plasma pharesis will take out the excess protein.

Smouldering myeloma
You may also hear the term 'smouldering myeloma'. This is a condition that is much the same as MGUS. The only difference is that the immunoglobulin levels are slightly higher than in MGUS. But they are not rising and the condition is usually stable for long periods of time. There is a risk that the condition will speed up and develop into full blown multiple myeloma.

How does one develop myeloma?
The cause of myeloma is not known. It is not inherited and it is not contagious. In common with other blood cancers there is an increased incidence in patients exposed to radiation.